Welcome to the Brain xQTL Serve

This is a resource for assessing the impact of genetic variation on multiple types of molecular traits derived from the human brain cortex:

xQTL pipeline

Reference

Ng B, White CC, Klein H, Patrick E, Xu J, Gaiteri C, Bennett D, Mostafavi S*, De Jager PL*. “Brain xQTL map: integrating the genetic architecture of the human brain transcriptome and epigenome.” [In Review]

*co-senior authors

Download

Lists of significant and genome-wide associations, results of mediation analysis and cell-specificity test, as well as code for x-QTL-weighted GWAS are available:

Explore associations between SNPs and molecular traits in your browser!

You can qeury our data in two ways: by providing a (i) SNP rsID, or a (ii) gene symbol.

SNP Query

Query xQTL associations for a specific SNP.

SNP query »

Gene Query

Query SNPs associated with expression levels of a specific gene.

gene query »